Your connectors may not be fully plugged in correctly, but if that isn't the issue it might be the manufacturers fault. Try a hard restart if the connector reset isn't solving your problem. At that point if nothing works, you're going to have to get a new screen. If the same problem occurs, it isn't the screens, your phone is the problem.
From a series of phones that had this problem, it was conclusive that it dealt with the originality of the home button. This case only appeared when someone was going to restore their iPhone with a replaced home button. I have tried a new home button cable with the new button and nothing worked. If you have your original button, try to fix the problem that way first. If nothing happens then there isn't anything else that can be done. This problem is also due to the new update, it is possible that in the next update Apple will have a fix for this problem.