After tightening down screen, orange stress marks above home button

When my phone screen isn’t pressed into place and screwed down, it’s fine. But as soon as I press it in and screw it in at the two bottom screws, almost straight away an orange stress mark appears at the bottom, in the same place every time. I’ve tried removing every single piece of adhesive on the screen. Could it be because I’m not using my screen adhesive to put the screen back in place, and I’m only just pressing it in without the glue?