Focus not working when zooming in and cannot get macro to set?

When trying to focus/zoom the camera is not focusing like it used to. I've been playing with settings the last few wks & am not sure if I've turned something off or what? When I zoom in on something it's blurry and won't focus. I've tried multiple things and not getting anywhere. Macro won't set either. I click/push the "MF/flower" setting on the back where the ISO, timer etc are but it won't appear on the screen. The flower shows on the screen in Manual mode but it's grey. Signed frustrated...